This folder contains the raw data for the subunit exchange fits. Each of the two folders in this directory contains data for several temperatures. 

The folders (e.g. '22C') contain the actual spectra in .raw format. They can be opened using either MassLynx (Waters, proprietary) or using the free software Unidec (http://unidec.chem.ox.ac.uk). The last number in the filename before the .raw extension refers to the timepoint in the subunit exchange.

Files ending in _exchange.txt contain the extracted relative intensities of the exchanging species (extracted using unidec). Light refers to the number unlabelled subunits in a 12mer, Heavy refers to the number of C13-labelled subunits in the oligomers. The data are organized in columns corresponding to timpanist in the subunit exchange experiment.

Files ending in .trace are the predicted traces resulting from the fit of the subunit exchange model. The First column denotes the time in minutes. The other columns contain the relative intensities of all exchange species, going from 12 light subunits and 0 heavy subunits on the left to 0 light and 12 heavy subunits. The first time point in the fit can differ from the value reported in the _exchange.txt file. This is a free parameter in the model that allows for a delay between the mixing of heavy and light subunits at the start of the reaction and that time point being flash frozen. 

The _extracted_rate_constansts.text file contains fitted off rate constants for both dimer and monomer dissociation for all temperatures. 
